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For a cash-pay hormone, weight-loss or functional practice, OptiMantra fits better than SimplePractice or Tebra, because it puts lab ordering, memberships, packages and telehealth on one base plan. SimplePractice is built mainly for therapy practices and lists no lab ordering. Tebra is built for practices that bill insurance, sells by quote, and lists labs, e-prescribing and Fullscript but no memberships. All three provide a BAA, as of November 2026.
We are not affiliated with OptiMantra, SimplePractice or Tebra, we take no referral fees, and we don't sell software. Every claim below links to the vendor's own pages, checked on November 12, 2026. We describe how each vendor charges but don't print prices; open each pricing page for current figures. For more EHRs in the same format, see our EHR comparison reference page.
Side by side
| OptiMantra | SimplePractice | Tebra | |
|---|---|---|---|
| Plans | One base plan per practitioner, plus add-ons | Starter, Essential, Plus, plus add-ons | Packages sold by quote, per prescribing provider |
| Intake forms | Custom questionnaires and consents through the portal | Paperless intake through the client portal | Digital patient intake |
| Online booking | On the base plan | Online appointment requests | Online scheduling in the Patient Experience packages |
| Payments | Point of sale and integrated payments; Fiserv or Stripe | Online payments and AutoPay | Tebra Payments: card on file, online payments, payment links |
| Memberships and packages | Recurring memberships and prepaid packages on the base plan | Not listed | Not listed; recurring payments are mentioned |
| Lab ordering | Labcorp, Quest, Access, Rupa Health, Boston Heart, Evexia and others | Not listed | eLabs with Labcorp, Quest, BioReference and others |
| Supplement dispensary | Fullscript and Wholescripts | Not listed | Fullscript, at no extra charge |
| E-prescribing | eRx license with EPCS, add-on | ePrescribe add-on with a one-time setup fee | eRx in the EHR packages; one-time EPCS setup fee per provider |
| Telehealth | On the base plan | Included; group telehealth on Plus | In the Practice Automation and EHR+ packages |
| Patient portal and messaging | On the base plan | Client portal; secure messaging on Essential and Plus | Patient portal with secure messages |
| Reminders | Automated text and email on the base plan; two-way texting add-on | Text, email and voice on Essential and Plus | Basic reminders in practice management; custom reminders in Patient Experience |
| API or integrations | Outbound webhooks; HighLevel and Zoho | Not listed | Built-in integrations; no public API on the pricing or FAQ pages |
| BAA | Published; signed when the trial converts | Agreed to when you create the account | Included in your agreement |
Who is each one built for?
These three serve different kinds of practice. That matters more than any single feature.
- OptiMantra is built for cash-based integrative, hormone, IV and functional practices. Its pricing page lists memberships, packages, custom compounding and IVs on the base plan.
- SimplePractice is built mainly for therapists and other private-practice clinicians. Its pricing page lists AI tools for therapy notes and treatment planning, and an insurance add-on.
- Tebra combines Kareo's clinical and billing software with PatientPop's marketing tools, per its FAQ. Its packages center on claims, eligibility checks and patient statements.
Tebra still shows up often in our niche. When we read 385 small practice websites in November 2026, OptiMantra was on 11% and Tebra was on 8%.
How does pricing differ?
OptiMantra has one plan, SimplePractice has three tiers, and Tebra gives a quote.
- OptiMantra: a flat monthly fee for the first practitioner, a lower fee for each extra one, and add-ons for eRx, two-way texting, fax and an AI scribe. There is a 15-day free trial with no card, and the subscription is month to month with 30 days' notice. See our guide to OptiMantra pricing and plans.
- SimplePractice: Starter, Essential and Plus, with extra clinicians added on Plus. ePrescribe, AI note tools and an insurance service are add-ons. Its pricing page offers a free trial of up to 30 days and often shows an introductory discount.
- Tebra: no public prices. Its pricing page says the quote depends on provider count, features, setup needs and claim volume. Each subscription covers one prescribing provider, and non-clinical staff are unlimited. Tebra's FAQ says there is no self-serve free trial, only a demo.
Tebra's public pages don't state contract length. Ask for the term and the cancellation rules in writing before you sign.
OptiMantra vs SimplePractice
Choose OptiMantra over SimplePractice if you order labs, prescribe or sell memberships. SimplePractice is the simpler tool, but it is built for talk therapy, not medical care.
The gap is labs and programs. OptiMantra's integrations page lists Labcorp, Quest, Access Medical Lab, Rupa Health and more, plus Fullscript and Wholescripts. SimplePractice's pricing page lists no lab ordering, no supplement dispensary and no memberships or packages. A hormone practice on SimplePractice would order labs and bill programs in other tools.
SimplePractice does the basics well for a solo clinician. It has paperless intake, online booking and a client portal. Its help center's plan comparison puts telehealth and online appointment requests on every plan, and secure messaging and full text, email and voice reminders on Essential and Plus. ePrescribe is an add-on with a one-time setup fee.
On the BAA, SimplePractice's help center says you agree to it when you create your trial account, and you don't sign again when you subscribe.
OptiMantra vs Tebra
Choose OptiMantra over Tebra if you are cash-pay and want to be live in days on a month-to-month plan. Choose Tebra if insurance billing is a real part of your revenue.
Tebra covers the clinical side. Its EHR page lists online intake forms, e-prescribing, electronic lab orders, telehealth and a patient portal. Its help center's eLabs list includes Labcorp, Quest and BioReference. For Quest, the practice now has to request the connection from its own Quest representative. Tebra's Fullscript integration is available to all Tebra users at no extra charge.
The gaps for a cash-pay practice are programs and speed. Tebra's patient payments page covers cards on file, online payments and payment links, and mentions recurring payments. It does not mention memberships or packages. Tebra's FAQ says most practices complete setup within 10 weeks. OptiMantra's onboarding page says setup can take less than a week.
Tebra's packages also include things OptiMantra doesn't sell, such as web profiles, review requests and a Google Business Profile listing. If you want one vendor for your EHR and your marketing, that counts in Tebra's favor.
Tebra's FAQ says a BAA is included in your agreement, and it publishes the text.
Which handles intake, booking and reminders best?
All three send intake forms online and let patients book or request a visit. The difference is which plan you need.
OptiMantra includes online booking, custom questionnaires and automated text and email reminders on its base plan. SimplePractice includes full reminders from Essential up. Tebra puts basic reminders in its practice management packages and online scheduling and custom reminders in its Patient Experience packages, per its pricing page.
A reminder only reaches a patient who has booked. For the form itself, see what a good hormone or functional medicine intake form asks.
Do all three sign a BAA?
Yes. The way you get it differs.
- OptiMantra: it publishes its BAA, and its FAQ says you sign it when your trial converts to a paid account.
- SimplePractice: you agree to the BAA when you create the account.
- Tebra: the BAA is incorporated into its terms of service for customers that are covered entities.
The BAA covers only that vendor. Your form builder, texting app and email tool each need their own. Check them in our BAA checker.
Choose OptiMantra if
- you run a cash-pay hormone, weight-loss or functional practice that orders labs and prescribes
- you sell memberships, packages or a monthly program
- you want public pricing, a free trial and no long contract
Choose SimplePractice if
- most of your visits are counseling or coaching and you rarely order labs
- you want the simplest setup for one clinician and can handle labs and program billing elsewhere
- you already use it and only need to add e-prescribing
Choose Tebra if
- you bill insurance for a real share of visits and need claims, eligibility checks and statements
- you want your EHR, billing and online marketing from one vendor
- you are comfortable with a quote, a demo and a longer setup
Other common shortlists are covered in OptiMantra vs Charm and OptiMantra vs Practice Better vs Healthie. For what owners say after signing up, see our summary of OptiMantra reviews.
What none of the three does
All three are built around booked patients. None will reply to a new inquiry within minutes, chase an intake form left half done, follow up on an unpaid lab fee, or bring back a patient who paused their program. Those steps sit around the EHR, and they are where cash-pay practices lose the most patients. Our guide on reply time for new patient inquiries shows how much the first reply matters.
Whichever EHR you pick, to see where your own patients drop off, request a free patient journey map.
This is general information, not legal advice. Confirm BAA terms with each vendor.
Common questions
Is OptiMantra better than SimplePractice?
For a hormone, weight-loss or functional practice, yes. OptiMantra lists direct lab ordering, memberships, packages and supplement integrations. SimplePractice is built mainly for therapy and lists none of those on its pricing page, as of November 2026.
Is OptiMantra better than Tebra?
For a cash-pay practice, usually. OptiMantra has public pricing, a free trial, month-to-month terms and memberships on its base plan. Tebra is stronger if you bill insurance, and it bundles marketing tools, but it sells by quote and has no self-serve trial.
Can you order labs in SimplePractice?
SimplePractice's pricing page lists no lab ordering or lab integrations, as of November 2026. A practice that orders labs often would need a separate lab platform alongside it.
Does Tebra work for a cash-pay practice?
It can. Tebra lists intake, e-prescribing, lab orders, telehealth, card-on-file payments and a Fullscript integration. Its public pages don't mention memberships or packages, so ask how it would bill a monthly program before you sign.
Do SimplePractice and Tebra sign a BAA?
Yes. SimplePractice says you agree to its BAA when you create your account. Tebra says a BAA is included in your agreement and publishes the text. OptiMantra publishes its BAA and has you sign it when your trial converts.
What about OptiMantra vs Jane or Cerbo?
Jane is a booking-first system that lists no lab ordering or e-prescribing, so a prescribing practice would need other tools. Cerbo merged with OptiMantra in December 2025 and both are still offered. Our EHR comparison reference page covers both.